How Long Does Rejuran Last? Months, Sessions and Trip Days
Dr. Jong Seon Kim Β· Director, Gangnam HERA8 min readLast updated 
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Rejuran how long does it last: if you can only get to Seoul once or twice a year, will the effect still be there when you come back?
After a full course, commonly three sessions spaced two to four weeks apart, the smoother and better-hydrated skin is usually described as holding for about six months to a year. Many people keep it with a top-up session roughly every six months. A single session fades sooner, and the small bumps from the injections typically settle within one to three days.
Hello, I'm Dr. Jong Seon Kim, Director of Gangnam HERA Plastic Surgery Clinic in Seoul.
HERA is registered with Korea's Ministry of Health and Welfare to treat foreign patients, and a medical interpreter for your language is provided at no extra charge. Every treatment starts with a 1:1 consultation and a written estimate, and the doctor who consults with you is the one who injects you, so the person planning your sessions is the person doing them.
If you're trying to work out how many trips this would take, send your travel dates and one daylight photo of the area on WhatsApp, and ask how many sessions would make sense for your skin.
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Send us your question or a photo on WhatsApp and we will reply in English.
Rejuran how long does it last: what the months depend on
The six-to-twelve-month figure describes a course, and it moves with a few things you can mostly predict yourself.
- Sessions completed. One session gives a smaller change that fades faster. Each session in a course builds on the one before.
- Your starting skin. Late-twenties skin with mild dullness holds a result differently from sun-damaged skin in its fifties.
- The area. The thin skin under the eyes, treated with Rejuran I, behaves differently from the cheeks.
- Sun, smoking and sleep. UV exposure breaks down the same collagen the treatment supports. Daily sunscreen does more to keep the result than an extra session.
Most published studies on polynucleotides follow people for a few months, so the upper end of that range rests mainly on clinical experience rather than long trials. I'd rather you plan around the lower end and be pleased if it lasts longer.
Why does one session fade faster than a course?
Rejuran is a polynucleotide (PN) injection made from purified salmon DNA. It doesn't fill or hold space under the skin the way a filler does. The PN fragments are thought to act as a scaffold that supports the skin's own repair cells, the fibroblasts, which make collagen and help the skin hold water. Reviews of the research on PN and the related PDRN describe this as a regenerative effect that builds over weeks.
That timing explains the pattern. The glow you see in the first few days is partly fluid from the injections themselves, and it fades within the week. The texture change people come for usually shows two to four weeks later, as the skin responds. A second and third session land while that response is still under way, so a course holds longer than single visits repeated a year apart.
For the differences between the three versions, Rejuran, Rejuran HB and Rejuran I, our guide to the Rejuran polynucleotide skin booster in Korea goes through each one.
Is Rejuran right for your skin, or would something else serve you better?
Rejuran suits skin that is losing quality: fine crepey lines, rough texture, dryness, pores that look larger, the flat look of tired skin. It is also a reasonable choice under the eyes, where filler can look heavy, and what Rejuran around the eyes can and can't change covers that area in detail.
It does little for three common concerns, and I'd rather say so before you plan a trip around it:
- Pigment. Sunspots and melasma need a different approach. Read about pigment and skin whitening treatment in Korea or what a pico laser can realistically change.
- Sagging. If your jawline or cheeks have dropped, that is a support problem. Ultrasound lifting or threads address it, with their own trade-offs, and the side effects of Ultherapy are worth reading first.
- Lost volume. Hollow temples or deep folds need volume, which a skin booster doesn't add.
Many faces have more than one of these. Then the plan is about order: which concern matters most to you, and which treatment answers it.
What does a session include, and what changes the estimate?
You get the consultation with the doctor, the treatment itself and a written estimate before anything is injected. The price is the same for Korean and foreign patients, with no surcharge for foreigners.
What moves the figure for your case:
- Which version you need: Rejuran, Rejuran HB, or Rejuran I for the eye area.
- The area: full face, under the eyes only, or both.
- How many sessions you plan this trip and later.
- Whether it's combined with another treatment in the same visit.
Ask on WhatsApp what your plan would cost, and mention the area and how many sessions you have in mind. Deposit and payment method are settled after the consultation, so you can raise both in that same message.
How I keep the treatment in the doctor's hands
At HERA, the specialist who consults with you is the one who performs your treatment, and it is never handed off. Only genuine, approved products are used, and the sealed vial is opened in front of you, so you see what goes into your skin. We don't rush through high volumes, which matters with an injection placed point by point across the face.
How many days should you plan in Seoul?
Downtime is short. The spacing between sessions is what decides the length of your trip.
| When | What you'll usually see | What to plan |
|---|---|---|
| Same day | Small raised bumps at each injection point, some redness | Go back to your hotel; skip makeup until the next day |
| Day 2β3 | Bumps mostly flat; any bruise turning yellow | Sightseeing and dinners out |
| Day 7 | Bruising usually gone; texture still improving | Photos, meetings, the flight home |
For the first day or two it's generally sensible to skip the sauna, alcohol and hard workouts, and to use sunscreen from the next morning.
Avoid the day before your flight.
Book your session at least two or three days before you leave. If a bruise shows up, it has time to fade, and you're still in Seoul if you have a question about how it looks.
Say you live in Sydney and can come for ten days once a year. A three-session course won't fit, because the sessions need weeks between them. I'd put one session on day two of the trip, so the bumps and any bruise are gone well before you fly. If you're new to Rejuran, treat that as the start of a course, with the next session on a second trip a few weeks later. If you've already finished a course, one session per trip works as the top-up.
If you live a short flight away, in Tokyo, Taipei or Singapore, three trips three or four weeks apart is the most direct way to complete the course. A stay of about a month fits two sessions.
Risks and side effects to know
Bumps, redness, tenderness and small bruises at the injection points are the usual reactions, and they typically clear within a few days to a week. Less often, a small firm lump lasts longer. Infection is rare when the skin is cleaned properly before injecting. Responses differ from person to person.
As general medical guidance, wait or skip it if you have:
- An allergy to salmon or fish, because the PN is salmon-derived
- Active acne, a cold sore or any infection in the area
- A pregnancy, or you're breastfeeding
- A recent laser or peel on the same area, or a current isotretinoin course
If a bump grows, turns hot or painful, or anything looks infected after you fly home, see a doctor where you live promptly, and send a photo with your treatment date on WhatsApp as well.
Before you buy flights, message HERA on WhatsApp with the dates you're considering and when you last had Rejuran or another skin booster, and ask which day of your trip suits a session.
Book a consultation
Send us your question or a photo on WhatsApp and we will reply in English.
The treatment itself. If you want the clinical detail β who it suits, how a session runs, recovery and the honest limits β it is set out on our Rejuran page.
Visiting HERA in Gangnam
HERA is at 4F, 9 Seocho-daero 73-gil, Seocho-gu, Seoul, about a three-minute walk from Gangnam Station. Leave by Exit 9, walk along Seocho-daero, turn right onto Seocho-daero 73-gil, and take the external elevator of the Time Building to the fourth floor. The doctors' profiles and directions are on Gangnam HERA's English homepage.
The clinic is open 10:00β20:00 on Monday and Friday, 10:00β19:00 Tuesday to Thursday and 10:00β17:00 on Saturday, with lunch from 13:00 to 14:00. It is closed on Sundays and public holidays, so if you land on a Saturday evening, Monday is your first chance.
To start, one daylight photo of the area on WhatsApp is enough, with the question you most want answered, such as whether your skin needs a course or a single session. In the consultation, what matters most to me is whether your skin is losing quality or losing support, because that tells us whether Rejuran is the right tool for you at all.
FAQ
Frequently asked questions
Q1Does Rejuran HB last longer than regular Rejuran?
Rejuran HB is the version made with added hyaluronic acid, so it leans toward hydration. There is no strong evidence that it lasts meaningfully longer. The choice between versions is about what your skin needs, and the course and top-ups matter more for duration than the version.Q2When will I notice a difference after a session?
A slight plumpness in the first days is mostly fluid from the injections and fades within a week. The change in texture and fine lines usually shows two to four weeks after a session and builds with each session in a course.Q3Will my skin look worse than before when it wears off?
No. Rejuran doesn't cause a rebound. As the effect fades, your skin gradually returns toward how it would have aged anyway, which is why many people plan a top-up rather than starting over.Q4Can I fly the day after a session?
Medically, flying the next day is generally fine. Cabin air is dry, so moisturise. The reason to leave two or three days is cosmetic and practical: bumps may still show, and a bruise needs time to fade.Q5Can I combine Rejuran with a lifting treatment on the same trip?
In many cases, yes. The order and spacing of the two treatments are part of the plan made at the consultation, so mention on WhatsApp which other treatment you're considering when you send your dates.
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On YouTube
Hear it from the doctors before you fly
Our doctors explain HERA's main treatments, lifting, filler and skin boosters, on camera, so you know who you are meeting and how they think before you land in Seoul.
Korean audio Β· auto-translated captions available on YouTube
16 videos
- 6:24Filler
Dr. Kim and Dr. Lee sort out how fillers, collagen injections and skin boosters differ, and which concern each one is for.
Dr. Jong Β· Dr. Jong - 7:36Clinic & doctors
HERA podcast ep. 3 β Dr. Kim and Dr. Lee look at the same face and explain the treatments they would choose, and why.
Dr. Jong Β· Dr. Jong - 8:07Lifting
What APTOS threads are, who they are recommended for, and a real patient's treatment and before-and-after.
Dr. Jong - 5:44Lifting
How APTOS compares with other lifting threads, what recovery is like and how long results last.
Dr. Jong Β· Dr. Jong - 4:20Filler
Dr. Kim shows how injection technique changes with the amount of filler, and how filler dissolves.
Dr. Jong - 5:50Filler
What a hollow upper eyelid is, filler vs fat grafting, how long it lasts and what to watch for.
Dr. Jong - 5:20Filler
Dr. Kim breaks down lip proportion, volume and mouth corners using well-known Korean celebrities' lips as examples.
Dr. Jong - 5:39Skin & boosters
Hydration, pores, breakouts or tone β matching the skin booster to what your skin actually needs.
Dr. Jong - 6:05Skin & boosters
Dr. Lee explains how Lituo and CaHA work, how they are injected and how often.
Dr. Jong - 5:00Skin & boosters
What Juvelook Eye is, what it is used for, how many sessions it takes and how long it lasts.
Dr. Jong - 5:56Lifting
Why lines form around the eyes, which treatments are combined, and Eye Thermage vs Eye Ulthera.
Dr. Jong - 4:58Lifting
Why Dr. Lee cares about lifting, and what he looks at first when he sees a patient.
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Dr. Han talks about what matters most in a consultation and the approach behind every treatment.
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A tour of HERA's main devices and which skin concern β pores, texture or firmness β each one helps with.
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Three areas brides care about, recommended treatments, and what still works with a month to go.
Dr. Jong Β· Dr. Jong - 4:39Clinic & doctors
What an AI skin scan measures β wrinkles, pigment, firmness, pores β and why a doctor's consultation still matters.
Dr. Jong Β· Dr. Jong
Shorts
One question, under a minute
HERA TV
The doctors explain it on camera β then in writing
Each piece is written by the doctor from their own YouTube video: the patient question, why it happens and how we approach it.
6:24korean plla fillerKorean PLLA Filler? Filler vs Collagen Booster vs Skin Booster
Is PLLA a filler? Two Gangnam HERA doctors sort out the three injectable families that confuse most patients β filler, collagen boosters and skin boosters β and how to combine them by area.
Dr. Jong Seon Kim7 min read
4:21neck line fillerNeck Line Filler: One Treatment, Start to Follow-Up
A Gangnam plastic surgeon treats a young patient's two neck lines on camera β why the lines form, why they are filled slightly high at first, how much it hurts, and what the follow-up visit showed.
Dr. Jin Yi Han6 min read
5:39korean skin boosterKorean Skin Booster: How to Choose by Your Skin's Main Problem
There are so many Korean skin boosters that patients freeze. A Gangnam doctor sorts them by the four problems that matter β hydration, pores, inflammation and brightness β and names the one he would pick if he could only choose one.
Dr. Jong Seon Kim7 min read
HERA Journal
Keep reading
Skin boostersHow Long Does Rejuran Take? Chair Time, Bumps and Trip Days
A Rejuran visit usually takes half a day at most, and the small injection bumps typically flatten within one to three days. The full course takes longer: sessions are spaced two to four weeks apart.
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Skin boostersWhen Does Rejuran Start to Show? Bumps, Weeks and Your Flight
Rejuran's injection bumps usually settle in a day or two and hydration often shows within weeks, while texture changes build over a course. Dr. Jong Seon Kim on which day of your Seoul stay to book it.
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Skin boostersRejuran Recovery Day by Day: Bumps, Bruises and Your Flight
Most people see Rejuran bumps flatten within about a day and redness fade in one to two days; a bruise can take up to a week. Keep two to three days in Seoul after the injection.
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Visit us
Find Gangnam HERA
In Seocho-gu, Seoul, a three-minute walk from Gangnam Station Exit 9. Tap the map for directions.
Address
4F, 9 Seocho-daero 73-gil, Seocho-gu, Seoul, Republic of Korea
Opening Hours
Tuesday, Wednesday, and Thursday: 10:00 AM β 7:00 PM; Monday, Friday: 10:00 AM β 8:00 PM; Saturday: 10:00 AM β 5:00 PM; Lunch break: 1:00 PM β 2:00 PM; Closed on Sundays and public holidays
