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Microneedling with Exosomes: Why the Two Are Combined

Dr. Jong Seon KimDr. Jong Seon Kim Β· Director, Gangnam HERA4 min readLast updated
Microneedling with Exosomes: Why the Two Are Combined

I'm Dr. Jong Seon Kim, a plastic surgeon at Gangnam HERA in Seoul. Patients arrive asking for "exosomes" the way they used to ask for vitamin drips β€” as a product rather than a procedure. The question I get is always the same: "Does it actually do anything?" The answer depends almost entirely on how it is delivered, which is why we combine it with RF microneedling.

Why combine microneedling with exosomes at all?

Because exosomes applied to intact skin mostly stay on the surface. The outer layer is a barrier β€” that is its job. RF microneedling opens micro-channels through it with ultra-fine needles while delivering radiofrequency energy into the dermis. The exosome booster is then absorbed through those channels rather than sitting on top of them.

At HERA this is done as Potenza Exosome β€” Jeisys' Potenza RF microneedling with an ASCE+ exosome skin booster.

The procedure being performed at Gangnam HERA in Seoul
The procedure at HERA β€” performed by a licensed physician in our Gangnam clinic. Illustrative procedure photo, not a patient result.

What it treats

  • Enlarged pores and acne scarring
  • Rough or uneven surface texture
  • Redness and heat in acne-prone skin
  • A barrier weakened by environmental stress
  • Fine lines, through collagen stimulation and deep hydration

If acne scarring is your main concern, I have written separately about how we approach scars, because scar type changes the plan more than the device does.

Who it suits β€” and who it doesn't

It suits skin that breaks out, flushes easily, or has lost its barrier. It is not a lifting treatment and it will not tighten sagging. If your concern is laxity rather than texture, I will point you to lifting instead β€” using a texture treatment to chase laxity wastes your trip and your money.

Recovery and what to expect

The session takes about 30 minutes. Mild redness, warmth or slight swelling appears immediately and typically settles within a day or two. Sun protection afterwards is not optional β€” freshly needled skin pigments easily.

Results build across a series rather than from one visit, so if you are here for a short trip I will tell you honestly what a single session can and cannot achieve.

Treatment room at Gangnam HERA in Seoul
HERA's treatment rooms in Gangnam, Seoul.

How it differs from microneedling alone

Plain microneedling creates controlled injury and lets the skin repair itself. That works, but the repair draws only on what your skin already has. Adding radiofrequency puts energy into the dermis rather than just the surface, and adding a booster gives the repair extra material to work with. The three together are why we run it as one treatment rather than a needling session with a serum applied afterwards.

If your skin is healthy and your concern is mild texture, plain needling may genuinely be enough β€” and I will say so rather than sell you the larger package.

How many sessions, and how to space them

Skin remodels on its own clock. Sessions are spaced to let that happen rather than to fill a calendar, and the change you notice at the end of a series is usually larger than the change after any single visit. Patients who photograph themselves weekly see it; patients who look in the mirror daily rarely do.

If you are visiting Seoul for a week, we plan what one or two sessions can realistically start, and what you would continue at home or on a return trip. I will not pretend a single session does what a series does.

What patients ask me next

  • "Does it hurt?" Numbing cream is applied first and most patients describe pressure and heat rather than pain.
  • "Can I wear makeup after?" Give the channels time to close β€” I will give you a specific window rather than a general rule, because it depends on the depth we used.
  • "Is it safe for darker or sensitive skin?" Settings change with skin type, and this is precisely the kind of decision that should be a physician's rather than a fixed protocol.
Gangnam HERA in Seoul
Same price for local and international patients, with on-site English interpretation.

The honest limits

Exosome products are not all the same, and the evidence base is younger than the marketing suggests. What I can tell you plainly is what we use, why the delivery method matters, and that the treatment is repeated rather than one-and-done. If someone promises you a transformation from a single session, be careful.

The clinical detail of the procedure β€” who it suits, how a session runs, recovery and the honest limits β€” is set out on our Potenza Exosome page.

Book a consultation

If you would like me to look at your case, send us a message and we will arrange a consultation β€” in person in Gangnam, or by photo first if you are still abroad. An English interpreter joins every consultation, and you receive an itemised written estimate before anything begins. International and local patients pay exactly the same.

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FAQ

Frequently asked questions

  • Q1Why do exosomes need microneedling?
    Because intact skin is a barrier and exosomes applied on top of it mostly stay on the surface. RF microneedling opens micro-channels so the booster is absorbed into the dermis instead of sitting on it.
  • Q2What does Potenza Exosome treat?
    Enlarged pores, acne scarring, rough texture, redness and heat in acne-prone skin, a weakened barrier, and fine lines through collagen stimulation and deep hydration.
  • Q3How much downtime is there?
    Mild redness, warmth or slight swelling appears immediately and typically settles within a day or two. Sun protection afterwards is essential because freshly needled skin pigments easily.
  • Q4Is one session enough?
    No. Results build across a series rather than from a single visit. If you are in Seoul briefly I will tell you honestly what one session can and cannot achieve.
  • Q5Will it tighten sagging skin?
    No. This is a texture and regeneration treatment, not a lifting treatment. If laxity is your concern I will point you toward lifting instead.

Nazanin Kondori

Oct 2026

Received Botox from Dr Hoon on the forehead and crow feet, Dr Hoon was very attentive and talked me through the procedure and listening to my expectations of a natural look - the clinic is very clean, staff are helpful and attentive - overall a very good experience, highly recommended

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Niroy Wilkes

Oct 2026

Dr. Han Jin Yi, Jasmine and the team were so amazing. My appointment was on time. I had a skin analysis and a very thorough consultation. The translator, Jasmine was just wonderful and the Dr. too. Everyone was very professional β€”very communicative throughout the entire procedure. Numbing was fully adequate and very little pain during the procedure I felt very well taken care of thank you so much, HERA.

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Carine Na Koreia

Oct 2026

I visited Gangnam Hera Lifting & Filler Clinic β€” an experience that only Korea can offer! πŸ‡°πŸ‡·βœ¨ A modern treatment with real, visible results for the skin. I tried Tenthera 800 Lines Procedure: Face + Interior with Dr. Lee Jong Hoon, and it was such an interesting experience to see how advanced Korean aesthetic treatments have become. I’ve been living in Korea for over five years, and I’m always looking for the best aesthetic treatments, impeccable service, and highly professional care. Having English interpretation available also makes the whole experience much more comfortable and ensures a clear understanding of every step of the treatment.

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Emmey Chefero

Oct 2026

I visited Gangman Hera Clinic and received lip filler from Dr. Kim Jong Seon. I was greeted by Jasmine when we first arrived and she assisted in translating the entire visit for us. This clinic is so clean, professional, and every staff member was kind and welcoming. I felt safe and thoroughly enjoyed the treatment process as well as my results. We had a full consultation to answer any questions and concerns we had. I would recommend this clinic to anyone visiting Seoul looking to get a luxury treatment.

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ryleigh stearns-nixon

Oct 2026

I got my lip filler done and I’m in love!!! the doctor and staff are so helpful!! Foreigners are very welcome here. I had a lovely experience would definitely recommend!!

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Maria Lammy

Oct 2026

Dr. Kim Jong Seon was so patient and knowledgeable. He gave me expert recommendations and took great care for the Botox treatment. All the staff were so polite and helpful. Very easy English service!

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Su May Yap

Sep 2026

Excellent service from start to finish with interpreter Jasmine and treatment with Dr Han Jin Yi. They explained everything in detail even during the treatments each step. Thank you!

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Jarie Balbedina

Sep 2026

I went to Hera Clinic to get Titanium Lifting for my skin concerns including developing wrinkles and overall contouring. My doctor was Dr. Lee Jong Hoon and he was very kind and easy to talk to. He recommended the appropriate kJ for my skin condition after a thorough consultation. The procedure itself also went well, although I did felt a bit more heat than I expected. Overall, my experience was very comfortableβ€”also thanks to all the nice staff and interpreter who assisted me throughout my visit~

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Real stories

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On YouTube

Hear it from the doctors before you fly

Our doctors explain HERA's main treatments, lifting, filler and skin boosters, on camera, so you know who you are meeting and how they think before you land in Seoul.

Subscribe on YouTube

Korean audio Β· auto-translated captions available on YouTube

16 videos

  • 6:24Filler

    Dr. Kim and Dr. Lee sort out how fillers, collagen injections and skin boosters differ, and which concern each one is for.

    Dr. Jong Β· Dr. Jong

  • 7:36Clinic & doctors

    HERA podcast ep. 3 β€” Dr. Kim and Dr. Lee look at the same face and explain the treatments they would choose, and why.

    Dr. Jong Β· Dr. Jong

  • 8:07Lifting

    What APTOS threads are, who they are recommended for, and a real patient's treatment and before-and-after.

    Dr. Jong

  • 5:44Lifting

    How APTOS compares with other lifting threads, what recovery is like and how long results last.

    Dr. Jong Β· Dr. Jong

  • 4:20Filler

    Dr. Kim shows how injection technique changes with the amount of filler, and how filler dissolves.

    Dr. Jong

  • 5:50Filler

    What a hollow upper eyelid is, filler vs fat grafting, how long it lasts and what to watch for.

    Dr. Jong

  • 5:20Filler

    Dr. Kim breaks down lip proportion, volume and mouth corners using well-known Korean celebrities' lips as examples.

    Dr. Jong

  • 5:39Skin & boosters

    Hydration, pores, breakouts or tone β€” matching the skin booster to what your skin actually needs.

    Dr. Jong

  • 6:05Skin & boosters

    Dr. Lee explains how Lituo and CaHA work, how they are injected and how often.

    Dr. Jong

  • 5:00Skin & boosters

    What Juvelook Eye is, what it is used for, how many sessions it takes and how long it lasts.

    Dr. Jong

  • 5:56Lifting

    Why lines form around the eyes, which treatments are combined, and Eye Thermage vs Eye Ulthera.

    Dr. Jong

  • 4:58Lifting

    Why Dr. Lee cares about lifting, and what he looks at first when he sees a patient.

    Dr. Jong

  • 3:30Clinic & doctors

    Dr. Han talks about what matters most in a consultation and the approach behind every treatment.

    Dr. Jin

  • 5:29Skin & boosters

    A tour of HERA's main devices and which skin concern β€” pores, texture or firmness β€” each one helps with.

    Dr. Jong

  • 4:40Clinic & doctors

    Three areas brides care about, recommended treatments, and what still works with a month to go.

    Dr. Jong Β· Dr. Jong

  • 4:39Clinic & doctors

    What an AI skin scan measures β€” wrinkles, pigment, firmness, pores β€” and why a doctor's consultation still matters.

    Dr. Jong Β· Dr. Jong

Shorts

One question, under a minute

All Shorts
  • Each tip reaches a different depth, so the choice depends on the area and your skin.

  • More shots is not automatically better β€” it depends on the area you want treated.

  • Asked to pick three treatments for the same face β€” one doctor picked four.

  • Skin thickness, fat and sagging differ face to face β€” what the doctor checks in a consultation.

  • The difference between the three, explained simply.

  • What Lituo is and the reason behind its reputation.

  • No β€” the right thread depends on your face and the lift you want.

  • What sets MINT threads apart from other lifting threads.

  • A patient shares the concern before lifting and how it felt afterwards.

  • Dr. Lee in under a minute: what a natural lift means to him.

  • A one-minute introduction to Dr. Han.

  • Similar-sounding, different purposes: how to tell them apart.

Visit us

Find Gangnam HERA

In Seocho-gu, Seoul, a three-minute walk from Gangnam Station Exit 9. Tap the map for directions.

Address

4F, 9 Seocho-daero 73-gil, Seocho-gu, Seoul, Republic of Korea

Opening Hours

Tuesday, Wednesday, and Thursday: 10:00 AM – 7:00 PM; Monday, Friday: 10:00 AM – 8:00 PM; Saturday: 10:00 AM – 5:00 PM; Lunch break: 1:00 PM – 2:00 PM; Closed on Sundays and public holidays

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  • Same price for locals & foreigners
  • English interpreter on-site
  • MOHW-registered clinic